Aviva Systems Biology's CRSP6 antibody - N-terminal region (ARP34192_P050) is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Precipitation, ChIP, Immunohistochemistry, Immunoprecipitation, and Western Blot.
Description
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by CRSP6 is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors